ReproGenomics Mutants
Abnormal Post-testicular Structure/Function
| Gene | Family ID # | Chromosome | Chromosome Region* (Ensembl Build 33) |
Status | Post Date | |
| Flanking Markers | Base Pair | |||||
| repro33 | G1-538-5 | Chr 16 | D16Mit58 to D16Mit106 | 31121394-84904036 | Cryopreserved | 10/13/05 |
| Male Phenotype |
In vitro clinic: Low seminal vesicle weight, low epididymal sperm concentration, abnormal looped sperm tails (see 1), sperm have very low motilty, very low IVF success. Histology evaluation: Normal spermatogenesis (see 2). |
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| repro24 | G1-476-15 | Chr 1 | D1Mit100 to D1Mit113 | 143741638-171733320 | Cryopreserved | 12/03/2004 |
| Male Phenotype |
In vitro clinic: Low epididymal sperm concentration, low sperm motility, abnormally shaped sperm heads, no IVF success. Histology evaluation: Normal |
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| repro16 | G1-449-33 | Chr 8 | D8Mit100 to D8Mit359 | 55715457-71351071 | Cryopreserved | 1/15/04 |
| Male Phenotype |
In vitro clinic: Low epididymal sperm concentration, low sperm motility, abnormal sperm head shape and large sperm, poor IVF success. Histology evaluation: Abnormal spermiogenesis with few elongated spermatids in some tubules (see 1), abnormal heads (see 2), abnormal spermatid elongation (see 3) and abnormal cells in the epididymal lumen (see 4). |
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| repro15 | G1-449-32 | Chr 11 | D11Mit231 to D11Mit140 | 35481820-53956337 | Cryopreserved | 1/15/04 |
| Male Phenotype |
In vitro clinic: low body weight, all epididymal sperm have abnormal head morphology, no IVF success. Histology evaluation: Abnormal spermiogenesis with abnormal shaped spermatid heads abundant in testis (see 1), few elongated spermatids in some tubules (see 2), severe spermatogenesis impairment in some tubules (see 3); abnormal cells in the epididymal lumen (see 4). |
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