Gene Family ID # Chromosome Chromosome Region*
(NCBI Build 34)
Status Post Date
Flanking Markers Base Pair
repro36 G1-569-2 Chr 9 D9Mit71 to D9Mit103 50248563-60611959

Limited shelf availability

5/14/07
Male
Phenotype

In vitro clinic: Very low testis weight, low seminal vesicle weight, no epididymal sperm recovered.

Histology evaluation: Arrest of spermatogenesis during pachytene stage of meiotic prophase, some tubules are greatly depleted of germ cells (see 1).

Female
Phenotype

In vitro clinic: No oocytes recovered.

Histology evaluation: Tiny ovaries with no growing oocytes or follicles (see 2).

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1. Arrest of germ cells   2. Tiny ovary  
     
     

*The scope of our funding includes mapping of the mutation to a chromosomal region, but in most cases does not include cloning of the gene responsible for the infertile phenotype.