Gene Family ID # Chromosome Chromosome Region*
(NCBI Build 34)		 Status Post Date
Flanking Markers Base Pair
repro23 G1-476-14 Chr 7
 D7Mit266 to D7Mit247 23698649-32307081 Cryopreserved 1/18/05
Male
Phenotype

In vitro clinic: Very low testis weight, no epididymal sperm recovered.

Histology evaluation: Low/abnormal spermatocytes with arrest of spermatogenesis (see 1) predominantly at pachytene spermatocyte stage (see 2-3).

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1. Abnormal spermatogenesis  2. Pachytene spermatocyte arrest  3. Pachytene spermatocyte arrest 
     
     

*The scope of our funding includes mapping of the mutation to a chromosomal region, but in most cases does not include cloning of the gene responsible for the infertile phenotype.