| Gene | Family ID # | Chromosome | Chromosome Region* (NCBI Build 34) |
Status | Post Date | |
| Flanking Markers | Base Pair | |||||
| repro14 | G1-449-31 | Chr 5 | D5Mit338 to D5Mit25 | 107690857-112994570 | Cloning in progress, ReproGenomics |
5/14/07 |
| Male Phenotype |
In vitro clinic: Very low testis weight, no epididymal sperm recovered. Histology evaluation: Arrest of spermatogenesis predominantly at pachytene stage of meiotic prophase or meiotic division stage (see 1), some germ cells appear apoptotic (see 2). |
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| Female Phenotype |
In vitro clinic: No oocytes recovered. Histology evaluation: Tiny ovaries with no growing oocytes or follicles (see 3). |
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Instructions for viewing candidate genes for this mutant line
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| 1. Arrest of germ cells | 2. Apoptotic germ cells in metaphase | 3. Tiny ovary |
*The scope of our funding includes mapping of the mutation to a chromosomal region, but in most cases does not include cloning of the gene responsible for the infertile phenotype.
