| Gene | Family ID # | Chromosome | Chromosome Region* (NCBI Build 34) |
Status | Post Date | |
| Flanking Markers | Base Pair | |||||
| repro7 | G1-419-29 | Chr 17 | D17Mit113 to D17Mit197 | 10619362-18003802 | Cloning in progress, ReproGenomics |
5/14/07 |
| Male Phenotype |
In vitro clinic: Very low testis weight, no epididymal sperm recovered. Histology evaluation: Arrest of spermatogenesis during mid-pachytene stage of meiotic prophase (see 1), some seminiferous tubules are greatly depleted of germ cells (see 2). |
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| Female Phenotype |
In vitro clinic: No oocytes recovered. Histology evaluation: Tiny ovaries with few growing oocytes (see 3). |
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Instructions for viewing candidate genes for this mutant line
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| 1. Arrest of germ cells | 2. Some tubules are greatly depleted of germ cells | 3. Tiny ovary |
*The scope of our funding includes mapping of the mutation to a chromosomal region, but in most cases does not include cloning of the gene responsible for the infertile phenotype.
