| Gene | Family ID # | Chromosome | Chromosome Region* (NCBI Build 34) |
Status | Post Date | |
| Flanking Markers | Base Pair | |||||
| repro2 | G1-374-15 | Chr 5 | D5Mit68 to D5Mit65 | 118958939-122584115 | Cryopreserved | 5/14/07 |
| Male Phenotype |
In vitro clinic: Very low epididymal sperm concentration, many sperm have abnormally shaped heads or no heads, sperm tails are short or curled, no sperm motility, no IVF success. Histology evaluation: Abnormal spermiogenesis (see 1) characterized by abnormally shaped spermatid heads and abnormal tail morphology. Publication: Lessard C, Lothrop H, Schimenti JC, Handel MA. Mutagenesis-generated mouse models of human infertility with abnormal sperm. Hum Reprod. 2007 Jan;22(1):159-66. Epub 2006 Aug 18. |
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Instructions for viewing candidate genes for this mutant line
Select the descriptive text below to view a larger image:
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| 1. Abnormal spermatid heads | ||
*The scope of our funding includes mapping of the mutation to a chromosomal region, but in most cases does not include cloning of the gene responsible for the infertile phenotype.
